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5-Amino-1MQ

$70.00

5-Amino-1MQ (5-Amino-1-methylquinolinium) is a small molecule peptide that has been researched for its potential metabolic and weight-loss benefits. This compound acts primarily through modulation of the enzyme nicotinamide N-methyltransferase (NNMT), which plays a role in cellular metabolism and energy expenditure.

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All peptides offered by Resolve Peptides are produced through the lyophilization (freeze-drying) process, a method that preserves molecular stability during handling and transport for approximately 3–4 months. Once reconstituted with bacteriostatic water, the solution must be stored under refrigeration to maintain integrity, where it generally remains viable for up to 30 days. Lyophilization, also referred to as cryodesiccation, is a specialized dehydration technique in which the compound is frozen and then placed under reduced pressure. This causes the frozen water content to sublimate directly from solid ice to vapor, leaving behind a stable, crystalline peptide powder. The resulting white, porous material can be kept at room temperature until reconstitution is required. After delivery, peptides should be safeguarded from light exposure and stored in a cool environment. For short-term use spanning several days to weeks, refrigeration at or below 4°C (39°F) is recommended. While lyophilized peptides may remain structurally intact at room temperature for weeks, cold storage provides added assurance of stability for ongoing research. For extended preservation lasting months or years, ultra-low freezing is preferred. Storage at –80°C (–112°F) offers the most reliable option for maintaining peptide quality and consistency over long durations. For detailed guidance on peptide handling and storage protocols, please refer to: Peptide Storage Information – resolvepeptides.com For extended preservation, particularly for storage spanning multiple months to years, peptides are best kept in ultra-low freezers at approximately –80°C (–112°F). Under these long-term conditions, structural stability is maximized, ensuring peptides retain their quality and suitability for future research applications.

Description

Overview

NNMT is an enzyme involved in methylation and energy regulation. It is often overexpressed in obese and metabolically compromised individuals. 5-Amino-1MQ inhibits NNMT activity, which may reduce fat accumulation, improve insulin sensitivity, and increase the availability of nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for mitochondrial health and cellular energy.

Researchers suggest that 5-Amino-1MQ may enhance cellular metabolism, promote thermogenesis, and support fat oxidation. Because of its systemic actions on metabolic rate and glucose homeostasis, it has gained attention for obesity research and metabolic disorder treatment.

Chemical Makeup

  • Molecular Formula: C10H11N2O
  • Molecular Weight: 175.21 g/mol

Research and Clinical Studies

Fat Loss and Insulin Sensitivity

Studies suggest that inhibition of NNMT by 5-Amino-1MQ leads to improved metabolic profiles, including reductions in white adipose tissue. In rodent models, the peptide increased energy expenditure and induced fat loss without requiring dietary changes. Additionally, it may improve glucose uptake and enhance insulin sensitivity in peripheral tissues.

Muscle Preservation

Unlike traditional weight loss agents that may lead to muscle wasting, 5-Amino-1MQ appears to preserve lean muscle mass. This makes it a potential candidate for use in patients seeking body recomposition—losing fat while maintaining or gaining muscle.

NAD+ Production

Inhibition of NNMT results in more nicotinamide being available for NAD+ synthesis. Higher NAD+ levels support mitochondrial function, energy metabolism, DNA repair, and cellular longevity. This mechanism is one of the reasons 5-Amino-1MQ is being researched for anti-aging and performance enhancement applications.

Potential Applications

  • Obesity and metabolic syndrome research • Insulin resistance and type 2 diabetes • Fat loss and body recomposition • NAD+ optimization for anti-aging protocols • Enhancing energy and endurance performance

Note: This information is for educational and research purposes only. 5-Amino-1MQ is not approved for human use or consumption outside of clinical studies.

Disclaimer

All products offered by resolvepeptides.com are intended strictly for laboratory and scientific research purposes only. These products are not approved by the FDA, are not medicines or supplements, and are not sold for human consumption, medical treatment, or veterinary use. Any discussion of potential benefits is based solely on preclinical findings.

Additional information

Weight 0.005 g
Strength (mg/vial)

5 mg

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Resolve Peptides provides peptides strictly for laboratory research and scientific studies.  All products sold on this website are intended for research use only and are not for human or animal consumption, medical use, diagnosis, or treatment.

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